Molecule and Cellular Biology 5

Points for the lecture

1. Gene regulation by manipulation of DNA structure (bending, looping, twisting)
2. Activation does not always involve direct interaction with RNAP
3. Genomes are packaged and spatially organized

• Reading: 8.3

DNA Looping and Post-Translation Modification (PTM)

Glutamine Synthesis

Unknown

NtrC Controls glnA Promoter from a Distance & How Does a Distant Element Works?

Unknown

Enhancers Function Over Long Distances
loop require the ATP and a littel amout of DNA

NtrC RNAP-Interactions Prefer a 390-bpIntervening Sequence	DNA Looping, in general, Requires >250 b.p.