Brownian Motion© Karobben

Brownian Motion

Brownian motion is the random and erratic movement of small particles in a fluid or gas due to collisions with molecules in the surrounding medium. It was first observed and explained by Robert Brown in 1827, and is an important concept in the study of diffusion and stochastic processes. Who said this?
Read more
RNA-structure and Prediction© Karobben

RNA-structure and Prediction

RNA structure research is important for understanding RNA function and regulation, as the structure of RNA molecules can impact their interactions with other molecules, such as proteins and small molecules, and influence gene expression and protein synthesis. Who sad this?
Read more
Wet Lab Techs with Brief Explained© Karobben
KEGG API© Karobben

KEGG API

Learning KEGG API is important for accessing and integrating biological pathway data, enabling researchers to analyze and visualize complex biological systems, identify new potential drug targets, and explore the relationships between genes, proteins, and metabolic pathways. Who sad this?
Read more

Venn Plot in R

Venn plot is a visualization tool to display overlapping or unique sets between two or more groups. In R, the 'VennDiagram' package provides an easy-to-use interface to create Venn plots with customizable colors, labels, and shapes. Who sad this?
Read more

FPKM, RPKM, CPM, TPM, TMM in RNA-Seq

RNA-seq expression normalization is the process of adjusting the raw gene expression counts to account for differences in sequencing depth and other technical factors. It is important to perform normalization to enable comparisons between samples and increase the accuracy and reproducibility of downstream analyses. Common normalization methods include TPM, FPKM, and DESeq. Who sad this?
Read more
Gene Set Enrichment Analysis (GESA) in R© Karobben

Gene Set Enrichment Analysis (GESA) in R

Gene Set Enrichment Analysis (GSEA) is a powerful tool for interpreting gene expression data in the context of predefined biological pathways and gene sets. It allows researchers to identify enriched gene sets, discover new relationships between genes, and gain insights into the underlying biological mechanisms. Who sad this?
Read more
Dash-bio, powered by plotly, python© Karobben

Dash-bio, powered by plotly, python

Dash-bio is a library that enables the creation of interactive, dynamic dashboards for exploring and analyzing biological data using Plotly Dash. With its customizable components and support for various data formats, dash-bio is a convenient tool for bioinformatics professionals and researchers Who sad this?
Read more

Regulatory RNA

Regulatory RNA refers to non-coding RNA molecules that play a role in regulating gene expression. These molecules can control gene expression by interacting with DNA and/or mRNA, influencing the process of transcription and translation. Examples of regulatory RNA include microRNAs, siRNAs, and long non-coding RNAs. Who sad this?
Read more

Short reads aligner compartment

The choice of software for aligning short reads in NGS can have a significant impact on the results. Different software programs use different algorithms for aligning reads and handling mismatches, leading to different levels of accuracy and sensitivity. Some software may prioritize speed, while others may prioritize accuracy, and still others may have specific strengths or limitations in handling certain types of data. It's important to carefully consider the characteristics and limitations of each software before making a choice to ensure the best possible alignment results Who sad this?
Read more

Riboviria, Something you'd like to know

Riboviruses are a type of RNA virus that infect bacteria. They have a unique replication strategy, using the host bacteria's own machinery to replicate their RNA genome. Riboviruses are thought to have potential as therapeutic agents, as they can specifically target harmful bacteria while leaving beneficial bacteria unharmed. Some studies have even explored using riboviruses as a new way to treat antibiotic-resistant bacterial infections. Who sad this?
Read more

Slurm Workload Manager

SLURM (Simple Linux Utility for Resource Management) is an open-source, highly scalable, and highly customizable cluster management and job scheduling system. It is widely used for managing high-performance computing (HPC) systems, allowing users to efficiently allocate resources, manage workloads, and monitor job progress. SLURM provides a simple and flexible interface for submitting, scheduling, and managing large-scale computing jobs, making it a popular choice for researchers, engineers, and other HPC users. Who sad this?
Read more
False Positives Made by Trinity© Trinity

False Positives Made by Trinity

Trinity is a popular RNA-Seq assembly tool that can generate false positive results due to several reasons, such as incomplete or low-quality data, presence of genomic contaminants, low expression levels of certain transcripts, or technical artifacts. Improper usage of parameters and a lack of proper quality control can also lead to false positive results in the assembly process Who sad this?
Read more

Common Contaminants in NGS

The bacterial populations in UPW systems used in the semiconductor industry were studied, including 2 university and 4 full-scale industrial plants in different locations. Samples were taken from the polishing section, which can impact the quality of UPW used in the final stages of semiconductor production. These results provide an overview of the general bacterial diversity in UPW production. Who sad this?
Read more